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The role of drug transporters in the kidney: lessons from tenofovir
Tenofovir disoproxil fumarate, the prodrug of nucleotide reverse transcriptase inhibitor tenofovir, shows high efficacy and relatively low toxicity in HIV patients. However, long-term kidney toxicity is now acknowledged as a modest but significant risk for tenofovir-containing regimens, and continuo...
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| 出版年: | Front Pharmacol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2014
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4227492/ https://ncbi.nlm.nih.gov/pubmed/25426075 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00248 |
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