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Computer-Aided Targeting of the PI3K/Akt/mTOR Pathway: Toxicity Reduction and Therapeutic Opportunities

The PI3K/Akt/mTOR pathway plays an essential role in a wide range of biological functions, including metabolism, macromolecular synthesis, cell growth, proliferation and survival. Its versatility, however, makes it a conspicuous target of many pathogens; and the consequential deregulations of this p...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Li, Tan, Wang, Guanyu
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227251/
https://ncbi.nlm.nih.gov/pubmed/25334061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms151018856
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