Liver X receptor β activation induces pyroptosis of human and murine colon cancer cells

Liver X receptors (LXRs) have been proposed to have some anticancer properties, through molecular mechanisms that remain elusive. Here we report for the first time that LXR ligands induce caspase-1-dependent cell death of colon cancer cells. Caspase-1 activation requires Nod-like-receptor pyrin doma...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell Death Differ
Autors principals: Derangère, V, Chevriaux, A, Courtaut, F, Bruchard, M, Berger, H, Chalmin, F, Causse, S Z, Limagne, E, Végran, F, Ladoire, S, Simon, B, Boireau, W, Hichami, A, Apetoh, L, Mignot, G, Ghiringhelli, F, Rébé, C
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
Matèries:
Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227150/
https://ncbi.nlm.nih.gov/pubmed/25124554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.117
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars