Human ectonucleotidase-expressing CD25(high) Th17 cells accumulate in breast cancer tumors and exert immunosuppressive functions

Th17 cells contribute to the development of some autoimmune and allergic diseases by driving tissue inflammation. However, the function of Th17 cells during cancer progression remains controversial. Here, we show that human memory CD25(high) Th17 cells suppress T cell immunity in breast cancer. Ecto...

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Publicat a:Oncoimmunology
Autors principals: Thibaudin, Marion, Chaix, Marie, Boidot, Romain, Végran, Frédérique, Derangère, Valentin, Limagne, Emeric, Berger, Hélène, Ladoire, Sylvain, Apetoh, Lionel, Ghiringhelli, François
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760277/
https://ncbi.nlm.nih.gov/pubmed/26942062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1055444
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