Human ectonucleotidase-expressing CD25(high) Th17 cells accumulate in breast cancer tumors and exert immunosuppressive functions

Th17 cells contribute to the development of some autoimmune and allergic diseases by driving tissue inflammation. However, the function of Th17 cells during cancer progression remains controversial. Here, we show that human memory CD25(high) Th17 cells suppress T cell immunity in breast cancer. Ecto...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Thibaudin, Marion, Chaix, Marie, Boidot, Romain, Végran, Frédérique, Derangère, Valentin, Limagne, Emeric, Berger, Hélène, Ladoire, Sylvain, Apetoh, Lionel, Ghiringhelli, François
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760277/
https://ncbi.nlm.nih.gov/pubmed/26942062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1055444
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