Human ectonucleotidase-expressing CD25(high) Th17 cells accumulate in breast cancer tumors and exert immunosuppressive functions

Th17 cells contribute to the development of some autoimmune and allergic diseases by driving tissue inflammation. However, the function of Th17 cells during cancer progression remains controversial. Here, we show that human memory CD25(high) Th17 cells suppress T cell immunity in breast cancer. Ecto...

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Dettagli Bibliografici
Pubblicato in:Oncoimmunology
Autori principali: Thibaudin, Marion, Chaix, Marie, Boidot, Romain, Végran, Frédérique, Derangère, Valentin, Limagne, Emeric, Berger, Hélène, Ladoire, Sylvain, Apetoh, Lionel, Ghiringhelli, François
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2015
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760277/
https://ncbi.nlm.nih.gov/pubmed/26942062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2015.1055444
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