Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly

Stress granules (SGs) are mRNA-protein aggregates induced during stress, which accumulate in many neurodegenerative diseases. Previously, the autophagy-lysosome pathway and valosin-containing protein (VCP), key players of the protein quality control (PQC), were shown to regulate SG degradation. This...

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Detaylı Bibliyografya
Yayımlandı:Cell Death Differ
Asıl Yazarlar: Seguin, S J, Morelli, F F, Vinet, J, Amore, D, De Biasi, S, Poletti, A, Rubinsztein, D C, Carra, S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2014
Konular:
Original Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227144/
https://ncbi.nlm.nih.gov/pubmed/25034784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.103
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