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SVIP Induces Localization of p97/VCP to the Plasma and Lysosomal Membranes and Regulates Autophagy

The small p97/VCP-interacting protein (SVIP) functions as an inhibitor of the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway. Here we show that overexpression of SVIP in HeLa cells leads to localization of p97/VCP at the plasma membrane, intracellular foci and juxtanuclear vacuoles...

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Hlavní autoři: Wang, Yang, Ballar, Petek, Zhong, Yongwang, Zhang, Xuebao, Liu, Chao, Zhang, Ying-Jiu, Monteiro, Mervyn J., Li, Jun, Fang, Shengyun
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164199/
https://ncbi.nlm.nih.gov/pubmed/21909394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024478
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