SVIP Induces Localization of p97/VCP to the Plasma and Lysosomal Membranes and Regulates Autophagy

The small p97/VCP-interacting protein (SVIP) functions as an inhibitor of the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway. Here we show that overexpression of SVIP in HeLa cells leads to localization of p97/VCP at the plasma membrane, intracellular foci and juxtanuclear vacuoles...

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Detalhes bibliográficos
Main Authors: Wang, Yang, Ballar, Petek, Zhong, Yongwang, Zhang, Xuebao, Liu, Chao, Zhang, Ying-Jiu, Monteiro, Mervyn J., Li, Jun, Fang, Shengyun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164199/
https://ncbi.nlm.nih.gov/pubmed/21909394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024478
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