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Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly
Stress granules (SGs) are mRNA-protein aggregates induced during stress, which accumulate in many neurodegenerative diseases. Previously, the autophagy-lysosome pathway and valosin-containing protein (VCP), key players of the protein quality control (PQC), were shown to regulate SG degradation. This...
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| 出版年: | Cell Death Differ |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Nature Publishing Group
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4227144/ https://ncbi.nlm.nih.gov/pubmed/25034784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.103 |
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