Inhibition of autophagy, lysosome and VCP function impairs stress granule assembly

Stress granules (SGs) are mRNA-protein aggregates induced during stress, which accumulate in many neurodegenerative diseases. Previously, the autophagy-lysosome pathway and valosin-containing protein (VCP), key players of the protein quality control (PQC), were shown to regulate SG degradation. This...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Cell Death Differ
Glavni autori: Seguin, S J, Morelli, F F, Vinet, J, Amore, D, De Biasi, S, Poletti, A, Rubinsztein, D C, Carra, S
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Original Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227144/
https://ncbi.nlm.nih.gov/pubmed/25034784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.103
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items