Syndecan-3 is selectively pro-inflammatory in the joint and contributes to antigen-induced arthritis in mice

INTRODUCTION: Syndecans are heparan sulphate proteoglycans expressed by endothelial cells. Syndecan-3 is expressed by synovial endothelial cells of rheumatoid arthritis (RA) patients where it binds chemokines, suggesting a role in leukocyte trafficking. The objective of the current study was to exam...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Kehoe, Oksana, Kalia, Neena, King, Sophie, Eustace, Andrew, Boyes, Charlotte, Reizes, Ofer, Williams, Anwen, Patterson, Angela, Middleton, Jim
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227035/
https://ncbi.nlm.nih.gov/pubmed/25015005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4610
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