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Constitutive- and accelerated shedding of murine syndecan-1 is mediated by cleavage of its core protein at a specific juxtamembrane site

Syndecan-1 is a developmentally regulated cell surface heparan sulfate proteoglycan (HSPG). It functions as a coreceptor for a variety of soluble and insoluble ligands and is implicated in several biological processes, including differentiation, cell migration, morphogenesis, and recently feeding be...

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Bibliographic Details
Main Authors: Wang, Zihua, Götte, Martin, Bernfield, Merton, Reizes, Ofer
Format: Artigo
Language:Inglês
Published: 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2546870/
https://ncbi.nlm.nih.gov/pubmed/16156648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi050620i
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