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Insulator function and topological domain border strength scale with architectural protein occupancy

BACKGROUND: Chromosome conformation capture studies suggest that eukaryotic genomes are organized into structures called topologically associating domains. The borders of these domains are highly enriched for architectural proteins with characterized roles in insulator function. However, a majority...

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Detalles Bibliográficos
Publicado en:Genome Biol
Main Authors: Van Bortle, Kevin, Nichols, Michael H, Li, Li, Ong, Chin-Tong, Takenaka, Naomi, Qin, Zhaohui S, Corces, Victor G
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226948/
https://ncbi.nlm.nih.gov/pubmed/24981874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-5-r82
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