Insulator function and topological domain border strength scale with architectural protein occupancy

BACKGROUND: Chromosome conformation capture studies suggest that eukaryotic genomes are organized into structures called topologically associating domains. The borders of these domains are highly enriched for architectural proteins with characterized roles in insulator function. However, a majority...

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Xehetasun bibliografikoak
Argitaratua izan da:Genome Biol
Egile Nagusiak: Van Bortle, Kevin, Nichols, Michael H, Li, Li, Ong, Chin-Tong, Takenaka, Naomi, Qin, Zhaohui S, Corces, Victor G
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2014
Gaiak:
Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226948/
https://ncbi.nlm.nih.gov/pubmed/24981874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-5-r82
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