Insulator function and topological domain border strength scale with architectural protein occupancy

BACKGROUND: Chromosome conformation capture studies suggest that eukaryotic genomes are organized into structures called topologically associating domains. The borders of these domains are highly enriched for architectural proteins with characterized roles in insulator function. However, a majority...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genome Biol
Prif Awduron: Van Bortle, Kevin, Nichols, Michael H, Li, Li, Ong, Chin-Tong, Takenaka, Naomi, Qin, Zhaohui S, Corces, Victor G
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2014
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226948/
https://ncbi.nlm.nih.gov/pubmed/24981874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2014-15-5-r82
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