Intense Androgen-Deprivation Therapy With Abiraterone Acetate Plus Leuprolide Acetate in Patients With Localized High-Risk Prostate Cancer: Results of a Randomized Phase II Neoadjuvant Study

PURPOSE: Cure rates for localized high-risk prostate cancers (PCa) and some intermediate-risk PCa are frequently suboptimal with local therapy. Outcomes are improved by concomitant androgen-deprivation therapy (ADT) with radiation therapy, but not by concomitant ADT with surgery. Luteinizing hormone...

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Pubblicato in:J Clin Oncol
Autori principali: Taplin, Mary-Ellen, Montgomery, Bruce, Logothetis, Christopher J., Bubley, Glenn J., Richie, Jerome P., Dalkin, Bruce L., Sanda, Martin G., Davis, John W., Loda, Massimo, True, Lawrence D., Troncoso, Patricia, Ye, Huihui, Lis, Rosina T., Marck, Brett T., Matsumoto, Alvin M., Balk, Steven P., Mostaghel, Elahe A., Penning, Trevor M., Nelson, Peter S., Xie, Wanling, Jiang, Zhenyang, Haqq, Christopher M., Tamae, Daniel, Tran, NamPhuong, Peng, Weimin, Kheoh, Thian, Molina, Arturo, Kantoff, Philip W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2014
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ORIGINAL REPORTS
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226804/
https://ncbi.nlm.nih.gov/pubmed/25311217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2013.53.4578
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