Intense Androgen-Deprivation Therapy With Abiraterone Acetate Plus Leuprolide Acetate in Patients With Localized High-Risk Prostate Cancer: Results of a Randomized Phase II Neoadjuvant Study

PURPOSE: Cure rates for localized high-risk prostate cancers (PCa) and some intermediate-risk PCa are frequently suboptimal with local therapy. Outcomes are improved by concomitant androgen-deprivation therapy (ADT) with radiation therapy, but not by concomitant ADT with surgery. Luteinizing hormone...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Taplin, Mary-Ellen, Montgomery, Bruce, Logothetis, Christopher J., Bubley, Glenn J., Richie, Jerome P., Dalkin, Bruce L., Sanda, Martin G., Davis, John W., Loda, Massimo, True, Lawrence D., Troncoso, Patricia, Ye, Huihui, Lis, Rosina T., Marck, Brett T., Matsumoto, Alvin M., Balk, Steven P., Mostaghel, Elahe A., Penning, Trevor M., Nelson, Peter S., Xie, Wanling, Jiang, Zhenyang, Haqq, Christopher M., Tamae, Daniel, Tran, NamPhuong, Peng, Weimin, Kheoh, Thian, Molina, Arturo, Kantoff, Philip W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2014
Assuntos:
ORIGINAL REPORTS
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226804/
https://ncbi.nlm.nih.gov/pubmed/25311217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2013.53.4578
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