Intense Androgen-Deprivation Therapy With Abiraterone Acetate Plus Leuprolide Acetate in Patients With Localized High-Risk Prostate Cancer: Results of a Randomized Phase II Neoadjuvant Study

PURPOSE: Cure rates for localized high-risk prostate cancers (PCa) and some intermediate-risk PCa are frequently suboptimal with local therapy. Outcomes are improved by concomitant androgen-deprivation therapy (ADT) with radiation therapy, but not by concomitant ADT with surgery. Luteinizing hormone...

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Publicat a:J Clin Oncol
Autors principals: Taplin, Mary-Ellen, Montgomery, Bruce, Logothetis, Christopher J., Bubley, Glenn J., Richie, Jerome P., Dalkin, Bruce L., Sanda, Martin G., Davis, John W., Loda, Massimo, True, Lawrence D., Troncoso, Patricia, Ye, Huihui, Lis, Rosina T., Marck, Brett T., Matsumoto, Alvin M., Balk, Steven P., Mostaghel, Elahe A., Penning, Trevor M., Nelson, Peter S., Xie, Wanling, Jiang, Zhenyang, Haqq, Christopher M., Tamae, Daniel, Tran, NamPhuong, Peng, Weimin, Kheoh, Thian, Molina, Arturo, Kantoff, Philip W.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Clinical Oncology 2014
Matèries:
ORIGINAL REPORTS
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226804/
https://ncbi.nlm.nih.gov/pubmed/25311217
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2013.53.4578
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