p-21 activated kinase 4 promotes proliferation and survival of pancreatic cancer cells through AKT- and ERK-dependent activation of NF-κB pathway

Identification of novel molecular targets and understanding the mechanisms underlying the aggressive nature of pancreatic cancer (PC) remain prime focus areas of research. Here, we investigated the expression and pathobiological significance of p21-activated kinase 4 (PAK4), a gene that was earlier...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Tyagi, Nikhil, Bhardwaj, Arun, Singh, Ajay P., McClellan, Steven, Carter, James E., Singh, Seema
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2014
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226721/
https://ncbi.nlm.nih.gov/pubmed/25238288
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