The iron chelator Dp44mT inhibits hepatocellular carcinoma metastasis via N-Myc downstream-regulated gene 2 (NDRG2)/gp130/STAT3 pathway

Here we showed that hepatocellular carcinoma (HCC) cell lines with high metastatic potential had low levels of NDRG2. The iron chelator Dp44mT up-regulated NDRG2, suppressed epithelial-mesenchymal transition (EMT) and inhibited tumor metastasis in HCC having high metastatic potential. Also Dp44mT at...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Oncotarget
Hlavní autoři: Wang, Jiabei, Yin, Dalong, Xie, Changming, Zheng, Tongsen, Liang, Yingjian, Hong, Xuehui, Lu, Zhaoyang, Song, Xuan, Song, Ruipeng, Yang, Haiyan, Sun, Boshi, Bhatta, Nishant, Meng, Xianzhi, Pan, Shangha, Jiang, Hongchi, Liu, Lianxin
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2014
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226698/
https://ncbi.nlm.nih.gov/pubmed/25261367
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky