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Look Ma, no PCNA: how DNA polymerase ε synthesizes long stretches of DNA without a processivity factor
The long-awaited crystal structure of Saccharomyces cerevisiae DNA polymerase ε reveals a unique domain never before observed in family B DNA polymerases. This novel domain endows polymerase ε with a capacity for highly processive DNA synthesis.
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| Publicado no: | Nat Struct Mol Biol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4226222/ https://ncbi.nlm.nih.gov/pubmed/24389546 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2749 |
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