G protein-coupled receptor 56 regulates mechanical overload-induced muscle hypertrophy

Peroxisome proliferator-activated receptor gamma coactivator 1-alpha 4 (PGC-1α4) is a protein isoform derived by alternative splicing of the PGC1α mRNA and has been shown to promote muscle hypertrophy. We show here that G protein-coupled receptor 56 (GPR56) is a transcriptional target of PGC-1α4 and...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: White, James P., Wrann, Christiane D., Rao, Rajesh R., Nair, Sreekumaran K., Jedrychowski, Mark P., You, Jae-Sung, Martínez-Redondo, Vicente, Gygi, Steven P., Ruas, Jorge L., Hornberger, Troy A., Wu, Zhidan, Glass, David J., Piao, Xianhua, Spiegelman, Bruce M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4226111/
https://ncbi.nlm.nih.gov/pubmed/25336758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417898111
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