Comparative Study of 17-AAG and NVP-AUY922 in Pancreatic and Colorectal Cancer Cells: Are There Common Determinants of Sensitivity?()

The use of heat shock protein 90 (Hsp90) inhibitors is an attractive antineoplastic therapy. We wanted to compare the effects of the benzoquinone 17-allylamino-17-demethoxygeldanamycin (17-AAG, tanespimycin) and the novel isoxazole resorcinol–based Hsp90 inhibitor NVP-AUY922 in a panel of pancreatic...

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Publicado no:Transl Oncol
Main Authors: Mayor-López, Leticia, Tristante, Elena, Carballo-Santana, Mar, Carrasco-García, Estefanía, Grasso, Silvina, García-Morales, Pilar, Saceda, Miguel, Luján, Juan, García-Solano, José, Carballo, Fernando, de Torre, Carlos, Martínez-Lacaci, Isabel
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225658/
https://ncbi.nlm.nih.gov/pubmed/25389454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2014.08.001
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