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Molecules and mechanisms controlling the active DNA demethylation of the mammalian zygotic genome

The active DNA demethylation in early embryos is essential for subsequent development. Although the zygotic genome is globally demethylated, the DNA methylation of imprinted regions, part of repeat sequences and some gamete-specific regions are maintained. Recent evidence has shown that multiple pro...

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Detalhes bibliográficos
Publicado no:Protein Cell
Main Authors: Ma, Jun-Yu, Zhang, Teng, Shen, Wei, Schatten, Heide, Sun, Qing Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Higher Education Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225482/
https://ncbi.nlm.nih.gov/pubmed/25152302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-014-0095-3
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