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DNA 5-Methylcytosine Demethylation Activities of the Mammalian DNA Methyltransferases

Methylation at the 5-position of DNA cytosine on the vertebrate genomes is accomplished by the combined catalytic actions of three DNA methyltransferases (DNMTs), the de novo enzymes DNMT3A and DNMT3B and the maintenance enzyme DNMT1. Although several metabolic routes have been suggested for demethy...

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Autors principals: Chen, Chun-Chang, Wang, Keh-Yang, Shen, Che-Kun James
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610981/
https://ncbi.nlm.nih.gov/pubmed/23393137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.445585
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