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DNA 5-Methylcytosine Demethylation Activities of the Mammalian DNA Methyltransferases

Methylation at the 5-position of DNA cytosine on the vertebrate genomes is accomplished by the combined catalytic actions of three DNA methyltransferases (DNMTs), the de novo enzymes DNMT3A and DNMT3B and the maintenance enzyme DNMT1. Although several metabolic routes have been suggested for demethy...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chen, Chun-Chang, Wang, Keh-Yang, Shen, Che-Kun James
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3610981/
https://ncbi.nlm.nih.gov/pubmed/23393137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.445585
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