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Structure-Based Rational Design of Prodrugs To Enable Their Combination with Polymeric Nanoparticle Delivery Platforms for Enhanced Antitumor Efficacy**
Drug-loaded nanoparticles (NPs) are of particular interest for efficient cancer therapy due to their improved drug delivery and therapeutic index in various types of cancer. However, the encapsulation of many chemotherapeutics into delivery NPs is often hampered by their unfavorable physicochemical...
में बचाया:
में प्रकाशित: | Angew Chem Int Ed Engl |
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मुख्य लेखकों: | , , , , , , |
स्वरूप: | Artigo |
भाषा: | Inglês |
प्रकाशित: |
WILEY-VCH Verlag
2014
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विषय: | |
ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4225468/ https://ncbi.nlm.nih.gov/pubmed/25196427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201406685 |
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