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Structure-Based Rational Design of Prodrugs To Enable Their Combination with Polymeric Nanoparticle Delivery Platforms for Enhanced Antitumor Efficacy**

Drug-loaded nanoparticles (NPs) are of particular interest for efficient cancer therapy due to their improved drug delivery and therapeutic index in various types of cancer. However, the encapsulation of many chemotherapeutics into delivery NPs is often hampered by their unfavorable physicochemical...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Wang, Hangxiang, Xie, Haiyang, Wu, Jiaping, Wei, Xuyong, Zhou, Lin, Xu, Xiao, Zheng, Shusen
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225468/
https://ncbi.nlm.nih.gov/pubmed/25196427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201406685
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