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HIPK2 sustains apoptotic response by phosphorylating Che-1/AATF and promoting its degradation
Che-1/AATF is an RNA polymerase II-binding protein that is involved in the regulation of gene transcription, which undergoes stabilization and accumulation in response to DNA damage. We have previously demonstrated that following apoptotic induction, Che-1 protein levels are downregulated through it...
Shranjeno v:
izdano v: | Cell Death Dis |
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Main Authors: | , , , , , , , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Nature Publishing Group
2014
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4225224/ https://ncbi.nlm.nih.gov/pubmed/25210797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.381 |
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