CK2-mediated phosphorylation of Che-1/AATF is required for its pro-proliferative activity

BACKGROUND: Che-1/AATF (Che-1) is an RNA polymerase II binding protein involved in several cellular processes, including proliferation, apoptosis and response to stress. We have recently demonstrated that Che-1 is able to promote cell proliferation by sustaining global histone acetylation in multipl...

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Détails bibliographiques
Publié dans:J Exp Clin Cancer Res
Auteurs principaux: Catena, Valeria, Bruno, Tiziana, Iezzi, Simona, Matteoni, Silvia, Salis, Annalisa, Sorino, Cristina, Damonte, Gianluca, Fanciulli, Maurizio
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2021
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8281565/
https://ncbi.nlm.nih.gov/pubmed/34266450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-021-02038-x
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