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The anti-apoptotic factor Che-1/AATF links transcriptional regulation, cell cycle control, and DNA damage response
Che-1 is a RNA polymerase II binding protein involved in the transcriptional regulation of E2F target genes and in cell proliferation. Recently, it has been shown that Che-1 accumulates in cells responding to genotoxic agents such as Doxorubicin and ionizing radiation. The DNA damage-activated check...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1948887/ https://ncbi.nlm.nih.gov/pubmed/17634135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1747-1028-2-21 |
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