Combining Hypoxia and Bioreactor Hydrodynamics Boosts Induced Pluripotent Stem Cell Differentiation Towards Cardiomyocytes

Cardiomyocytes (CMs) derived from induced pluripotent stem cells (iPSCs) hold great promise for patient-specific disease modeling, drug screening and cell therapy. However, existing protocols for CM differentiation of iPSCs besides being highly dependent on the application of expensive growth factor...

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Dettagli Bibliografici
Pubblicato in:Stem Cell Rev
Autori principali: Correia, Cláudia, Serra, Margarida, Espinha, Nuno, Sousa, Marcos, Brito, Catarina, Burkert, Karsten, Zheng, Yunjie, Hescheler, Jürgen, Carrondo, Manuel J. T., Šarić, Tomo, Alves, Paula M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4225049/
https://ncbi.nlm.nih.gov/pubmed/25022569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12015-014-9533-0
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