Generation of human induced pluripotent stem cell-derived cardiomyocytes in 2D monolayer and scalable 3D suspension bioreactor cultures with reduced batch-to-batch variations

Human induced pluripotent stem cell derived cardiomyocytes (hiPSC-CMs) are promising candidates to treat myocardial infarction and other cardiac diseases. Such treatments require pure cardiomyocytes (CMs) in large quantities. Methods: In the present study we describe an improved protocol for product...

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Detalhes bibliográficos
Publicado no:Theranostics
Main Authors: Hamad, Sarkawt, Derichsweiler, Daniel, Papadopoulos, Symeon, Nguemo, Filomain, Šarić, Tomo, Sachinidis, Agapios, Brockmeier, Konrad, Hescheler, Jürgen, Boukens, Bastiaan J, Pfannkuche, Kurt
Formato: Artigo
Idioma:Inglês
Publicado em: Ivyspring International Publisher 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6831300/
https://ncbi.nlm.nih.gov/pubmed/31695764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.32058
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