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Establishing PAX6 as a Biomarker to Detect Early Loss of Ocular Phenotype in Human Patients With Sjögren's Syndrome

PURPOSE. Sjögren's syndrome (SS) is a common autoimmune disease that can cause aqueous-deficient dry eye and the aberrant differentiation of ocular mucosal epithelial cells toward a lineage that is pathologically keratinized and skin-like. PAX6 is the master regulator of corneal lineage commitm...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: McNamara, Nancy A., Gallup, Marianne, Porco, Travis C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224577/
https://ncbi.nlm.nih.gov/pubmed/25228544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14828
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