Loading...

Astaxanthin inhibits apoptosis in alveolar epithelial cells type II in vivo and in vitro through the ROS-dependent mitochondrial signalling pathway

Oxidative stress is an important molecular mechanism underlying lung fibrosis. The mitochondrion is a major organelle for oxidative stress in cells. Therefore, blocking the mitochondrial signalling pathway may be the best therapeutic manoeuver to ameliorate lung fibrosis. Astaxanthin (AST) is an exc...

Full description

Saved in:
Bibliographic Details
Published in:J Cell Mol Med
Main Authors: Song, Xiaodong, Wang, Bingsi, Lin, Shengcui, Jing, Lili, Mao, Cuiping, Xu, Pan, Lv, Changjun, Liu, Wen, Zuo, Ji
Format: Artigo
Language:Inglês
Published: BlackWell Publishing Ltd 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224554/
https://ncbi.nlm.nih.gov/pubmed/25215580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12347
Tags: Add Tag
No Tags, Be the first to tag this record!