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Astaxanthin inhibits apoptosis in alveolar epithelial cells type II in vivo and in vitro through the ROS-dependent mitochondrial signalling pathway
Oxidative stress is an important molecular mechanism underlying lung fibrosis. The mitochondrion is a major organelle for oxidative stress in cells. Therefore, blocking the mitochondrial signalling pathway may be the best therapeutic manoeuver to ameliorate lung fibrosis. Astaxanthin (AST) is an exc...
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Published in: | J Cell Mol Med |
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Main Authors: | , , , , , , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
BlackWell Publishing Ltd
2014
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4224554/ https://ncbi.nlm.nih.gov/pubmed/25215580 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12347 |
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