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Astaxanthin prevents pulmonary fibrosis by promoting myofibroblast apoptosis dependent on Drp1-mediated mitochondrial fission

Promotion of myofibroblast apoptosis is a potential therapeutic strategy for pulmonary fibrosis. This study investigated the antifibrotic effect of astaxanthin on the promotion of myofibroblast apoptosis based on dynamin-related protein-1 (Drp1)-mediated mitochondrial fission in vivo and in vitro. R...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Zhang, Jinjin, Xu, Pan, Wang, Youlei, Wang, Meirong, Li, Hongbo, Lin, Shengcui, Mao, Cuiping, Wang, Bingsi, Song, Xiaodong, Lv, Changjun
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4568926/
https://ncbi.nlm.nih.gov/pubmed/26119034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12609
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