Astaxanthin inhibits apoptosis in alveolar epithelial cells type II in vivo and in vitro through the ROS-dependent mitochondrial signalling pathway

Oxidative stress is an important molecular mechanism underlying lung fibrosis. The mitochondrion is a major organelle for oxidative stress in cells. Therefore, blocking the mitochondrial signalling pathway may be the best therapeutic manoeuver to ameliorate lung fibrosis. Astaxanthin (AST) is an exc...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Song, Xiaodong, Wang, Bingsi, Lin, Shengcui, Jing, Lili, Mao, Cuiping, Xu, Pan, Lv, Changjun, Liu, Wen, Zuo, Ji
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224554/
https://ncbi.nlm.nih.gov/pubmed/25215580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12347
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