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Top-Down Strategies for the Structural Elucidation of Intact Gram-negative Bacterial Endotoxins

Re-modelling of lipopolysaccharides, which are the primary constituent of the outer cell membrane of Gram-negative bacteria, modulates pathogenesis and resistance to microbials. Reported herein is the characterization of intact Gram-negative bacterial lipooligosaccharides (LOS) via a new strategy ut...

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Foilsithe in:Chem Sci
Main Authors: O’Brien, John P., Needham, Brittany D., Brown, Dusty B., Trent, M. Stephen, Brodbelt, Jennifer S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2014
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224326/
https://ncbi.nlm.nih.gov/pubmed/25386333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4SC01034E
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