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Top-Down Strategies for the Structural Elucidation of Intact Gram-negative Bacterial Endotoxins

Re-modelling of lipopolysaccharides, which are the primary constituent of the outer cell membrane of Gram-negative bacteria, modulates pathogenesis and resistance to microbials. Reported herein is the characterization of intact Gram-negative bacterial lipooligosaccharides (LOS) via a new strategy ut...

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Publicat a:Chem Sci
Autors principals: O’Brien, John P., Needham, Brittany D., Brown, Dusty B., Trent, M. Stephen, Brodbelt, Jennifer S.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224326/
https://ncbi.nlm.nih.gov/pubmed/25386333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C4SC01034E
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