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mGluR2/3 blockade produces rapid and long-lasting reversal of anhedonia caused by chronic stress exposure

BACKGROUND: Depression is a prevalent neuropsychiatric disorder that affects an estimated 350 million people worldwide. Currently available treatments for depression are lacking in both speed of onset and efficacy. Recent pharmacological efforts have targeted the glutamatergic neurotransmitter syste...

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Detalhes bibliográficos
Publicado no:J Mol Psychiatry
Main Authors: Dwyer, Jason M, Lepack, Ashley E, Duman, Ronald S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224009/
https://ncbi.nlm.nih.gov/pubmed/25408908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-9256-1-15
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