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Fast-Acting Antidepressants Rapidly Stimulate ERK Signaling and BDNF Release in Primary Neuronal Cultures

Recent preclinical and clinical studies demonstrate that three functionally different compounds, the NMDA receptor channel blocker ketamine, mGlu(2/3) receptor antagonist LY341495, and NMDA receptor glycine site agent GLYX-13 produce rapid and long lasting antidepressant effects. Furthermore, these...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuropharmacology
Prif Awduron: Lepack, Ashley E., Bang, Eunyoung, Lee, Boyoung, Dwyer, Jason M., Duman, Ronald S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075989/
https://ncbi.nlm.nih.gov/pubmed/27634096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2016.09.011
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