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Hypoxia represses microRNA biogenesis proteins in breast cancer cells

BACKGROUND: Cancers are commonly characterised by hypoxia and also by global reductions in the levels of mature microRNAs. We have examined the hypothesis that hypoxia might mediate this reduction through repressive effects on microRNA biogenesis proteins. METHODS: Breast cancer cell lines were expo...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Bandara, Veronika, Michael, Michael Z, Gleadle, Jonathan M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223767/
https://ncbi.nlm.nih.gov/pubmed/25052766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-533
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