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Hypoxia represses microRNA biogenesis proteins in breast cancer cells

BACKGROUND: Cancers are commonly characterised by hypoxia and also by global reductions in the levels of mature microRNAs. We have examined the hypothesis that hypoxia might mediate this reduction through repressive effects on microRNA biogenesis proteins. METHODS: Breast cancer cell lines were expo...

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Vydáno v:BMC Cancer
Hlavní autoři: Bandara, Veronika, Michael, Michael Z, Gleadle, Jonathan M
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223767/
https://ncbi.nlm.nih.gov/pubmed/25052766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-533
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