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Hypoxia represses microRNA biogenesis proteins in breast cancer cells

BACKGROUND: Cancers are commonly characterised by hypoxia and also by global reductions in the levels of mature microRNAs. We have examined the hypothesis that hypoxia might mediate this reduction through repressive effects on microRNA biogenesis proteins. METHODS: Breast cancer cell lines were expo...

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Publicat a:BMC Cancer
Autors principals: Bandara, Veronika, Michael, Michael Z, Gleadle, Jonathan M
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223767/
https://ncbi.nlm.nih.gov/pubmed/25052766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-14-533
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