Human iPSC Neurons Display Activity-Dependent Neurotransmitter Secretion: Aberrant Catecholamine Levels in Schizophrenia Neurons

This study investigated human-induced pluripotent stem cell (hiPSC) -derived neurons for their ability to secrete neurotransmitters in an activity-dependent manner, the fundamental property required for chemical neurotransmission. Cultured hiPSC neurons showed KCl stimulation of activity-dependent s...

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Bibliographic Details
Published in:Stem Cell Reports
Main Authors: Hook, Vivian, Brennand, Kristen J., Kim, Yongsung, Toneff, Thomas, Funkelstein, Lydiane, Lee, Kelly C., Ziegler, Michael, Gage, Fred H.
Format: Artigo
Language:Inglês
Published: Elsevier 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223699/
https://ncbi.nlm.nih.gov/pubmed/25358781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.08.001
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