Inducing Cellular Aging: Enabling Neurodegeneration-in-a-Dish

Por Brennand, Kristen J.
Publicado em 2013

Personalized medicine in a dish: the growing possibility of neuropsychiatric disease drug discovery tailored to patient genetic variants using stem cells

Por Brennand, Kristen J.
Publicado no Stem Cell Investig (2017)

Prospects for Modeling Abnormal Neuronal Function in Schizophrenia Using Human Induced Pluripotent Stem Cells

Por Prytkova, Iya, Brennand, Kristen J.
Publicado no Front Cell Neurosci (2017)

Modeling psychiatric disorders through reprogramming

Por Brennand, Kristen J., Gage, Fred H.
Publicado em 2012

Concise Review: The Promise of hiPSC-Based Studies of Schizophrenia

Por Brennand, Kristen J., Gage, Fred H.
Publicado em 2011

Using hiPSCs to Model Neuropsychiatric Copy Number Variations (CNVs) has Potential to Reveal Underlying Disease Mechanisms

Por Flaherty, Erin K., Brennand, Kristen J.
Publicado no Brain Res (2015)

Neural organoids for disease phenotyping, drug screening and developmental biology studies

Por Hartley, Brigham J., Brennand, Kristen J.
Publicado no Neurochem Int (2016)

Noncoding RNAs and neurobehavioral mechanisms in psychiatric disease

Por Kocerha, Jannet, Dwivedi, Yogesh, Brennand, Kristen J
Publicado no Mol Psychiatry (2015)

A Guide to Generating and Using hiPSC Derived NPCs for the Study of Neurological Diseases

Por Topol, Aaron, Tran, Ngoc N., Brennand, Kristen J.
Publicado no J Vis Exp (2015)

From “Directed Differentiation” to “Neuronal Induction”: Modeling Neuropsychiatric Disease

Por Ho, Seok-Man, Topol, Aaron, Brennand, Kristen J
Publicado no Biomark Insights (2015)

The Importance of Non-neuronal Cell Types in hiPSC-Based Disease Modeling and Drug Screening

Por Gonzalez, David M., Gregory, Jill, Brennand, Kristen J.
Publicado no Front Cell Dev Biol (2017)

Modeling Schizophrenia Using Induced Pluripotent Stem Cell–Derived and Fibroblast-Induced Neurons

Por Tran, Ngoc N., Ladran, Ian G., Brennand, Kristen J.
Publicado em 2013

Modeling heterogeneous patients with a clinical diagnosis of schizophrenia using induced pluripotent stem cells

Por Brennand, Kristen J., Landek-Salgado, Melissa A., Sawa, Akira
Publicado em 2013

Neural stem and progenitor cells in health and disease

Por Ladran, Ian, Tran, Ngoc, Topol, Aaron, Brennand, Kristen J.
Publicado em 2013

Evolving toward a human-cell based and multiscale approach to drug discovery for CNS disorders

Por Schadt, Eric E., Buchanan, Sean, Brennand, Kristen J., Merchant, Kalpana M.
Publicado no Front Pharmacol (2014)

Induced pluripotent stem cells (iPSCs) and neurological disease modeling: progress and promises

Por Marchetto, Maria C., Brennand, Kristen J., Boyer, Leah F., Gage, Fred H.
Publicado no Hum Mol Genet (2011)

Dopaminergic differentiation of schizophrenia hiPSCs

Por Hartley, Brigham J., Tran, Ngoc, Ladran, Ian, Reggio, Kathryn, Brennand, Kristen J.
Publicado no Mol Psychiatry (2015)

Activity-Dependent Changes in Gene Expression in Schizophrenia Human-Induced Pluripotent Stem Cell Neurons

Por Roussos, Panos, Guennewig, Boris, Kaczorowski, Dominik C., Barry, Guy, Brennand, Kristen J.
Publicado no JAMA Psychiatry (2016)

Modeling Neuropsychiatric and Neurodegenerative Diseases With Induced Pluripotent Stem Cells

Por LaMarca, Elizabeth A., Powell, Samuel K., Akbarian, Schahram, Brennand, Kristen J.
Publicado no Front Pediatr (2018)

Altered WNT signaling in hiPSC NPCs derived from four schizophrenia patients

Por Topol, Aaron, Zhu, Shijia, Tran, Ngoc, Simone, Anthony, Fang, Gang, Brennand, Kristen J.
Publicado no Biol Psychiatry (2015)