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Using hiPSCs to Model Neuropsychiatric Copy Number Variations (CNVs) has Potential to Reveal Underlying Disease Mechanisms
Schizophrenia is a neuropsychological disorder with a strong heritable component; genetic risk for schizophrenia is conferred by both common variants of relatively small effect and rare variants with high penetrance. Genetically engineered mouse models can recapitulate rare variants, displaying some...
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| Publicado no: | Brain Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4865445/ https://ncbi.nlm.nih.gov/pubmed/26581337 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2015.11.009 |
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