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Modeling psychiatric disorders through reprogramming

Psychiatric disorders, including autism spectrum disorders and schizophrenia, are extremely heritable complex genetic neurodevelopmental disorders. It is now possible to directly reprogram fibroblasts from psychiatric patients into human induced pluripotent stem cells (hiPSCs) and subsequently diffe...

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Bibliographic Details
Main Authors: Brennand, Kristen J., Gage, Fred H.
Format: Artigo
Language:Inglês
Published: The Company of Biologists Limited 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3255540/
https://ncbi.nlm.nih.gov/pubmed/21954066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.008268
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