Hypothalamic PGC-1α Protects Against High Fat Diet Exposure by Regulating ERα

High fat diets (HFD) lead to obesity and inflammation in the central nervous system. Estrogens and Estrogen Receptor alpha (ERα) protect premenopausal females from the metabolic complications of inflammation and obesity related disease. Here we demonstrate that hypothalamic PGC-1α regulates ERα and...

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Vydáno v:Cell Rep
Hlavní autoři: Morselli, Eugenia, Fuente-Martin, Esther, Finan, Brian, Kim, Min, Frank, Aaron, Garcia-Caceres, Cristina, Navas, Carlos Rodriguez, Gordillo, Ruth, Neinast, Michael, Kalainayakan, Sarada P., Gao, Yuanqing, Yi, Chun-Xia, Hahner, Lisa, Palmer, Biff F., Tschöp, Matthias H., Clegg, Deborah J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223650/
https://ncbi.nlm.nih.gov/pubmed/25373903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.09.025
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