Hypothalamic PGC-1α Protects Against High Fat Diet Exposure by Regulating ERα

High fat diets (HFD) lead to obesity and inflammation in the central nervous system. Estrogens and Estrogen Receptor alpha (ERα) protect premenopausal females from the metabolic complications of inflammation and obesity related disease. Here we demonstrate that hypothalamic PGC-1α regulates ERα and...

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Publicado no:Cell Rep
Main Authors: Morselli, Eugenia, Fuente-Martin, Esther, Finan, Brian, Kim, Min, Frank, Aaron, Garcia-Caceres, Cristina, Navas, Carlos Rodriguez, Gordillo, Ruth, Neinast, Michael, Kalainayakan, Sarada P., Gao, Yuanqing, Yi, Chun-Xia, Hahner, Lisa, Palmer, Biff F., Tschöp, Matthias H., Clegg, Deborah J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223650/
https://ncbi.nlm.nih.gov/pubmed/25373903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.09.025
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