Energy Stress Regulates Hippo–YAP Signaling involving AMPK-mediated Regulation of Angiomotin Like-1 Protein

Hippo signaling is a tumor suppressor pathway involved in organ size control and tumorigenesis, through the inhibition of YAP and TAZ. Here we show that energy stress induces YAP cytoplasmic retention and Ser127 phosphorylation and inhibits YAP transcriptional activity and YAP-dependent transformati...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Cell Rep
Päätekijät: DeRan, Michael, Yang, Jiayi, Shen, Che-Hung, Peters, Eric C., Fitamant, Julien, Chan, Puiyee, Hsieh, Mindy, Zhu, Shunying, Asara, John M., Zheng, Bin, Bardeesy, Nabeel, Liu, Jun, Wu, Xu
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223634/
https://ncbi.nlm.nih.gov/pubmed/25373897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2014.09.036
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia