Copper-catalyzed azide-alkyne cycloaddition (click chemistry)-based Detection of Global Pathogen-host AMPylation on Self-assembled Human Protein Microarrays

AMPylation (adenylylation) is a recently discovered mechanism employed by infectious bacteria to regulate host cell signaling. However, despite significant effort, only a few host targets have been identified, limiting our understanding of how these pathogens exploit this mechanism to control host c...

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Bibliographic Details
Published in:Mol Cell Proteomics
Main Authors: Yu, Xiaobo, Woolery, Andrew R., Luong, Phi, Hao, Yi Heng, Grammel, Markus, Westcott, Nathan, Park, Jin, Wang, Jie, Bian, Xiaofang, Demirkan, Gokhan, Hang, Howard C., Orth, Kim, LaBaer, Joshua
Format: Artigo
Language:Inglês
Published: The American Society for Biochemistry and Molecular Biology 2014
Subjects:
Technological Innovation and Resources
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223499/
https://ncbi.nlm.nih.gov/pubmed/25073739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M114.041103
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