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The Crystal Structure of the Adenylation Enzyme VinN Reveals a Unique β-Amino Acid Recognition Mechanism

Adenylation enzymes play important roles in the biosynthesis and degradation of primary and secondary metabolites. Mechanistic insights into the recognition of α-amino acid substrates have been obtained for α-amino acid adenylation enzymes. The Asp residue is invariant and is essential for the stabi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Miyanaga, Akimasa, Cieślak, Jolanta, Shinohara, Yuji, Kudo, Fumitaka, Eguchi, Tadashi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223343/
https://ncbi.nlm.nih.gov/pubmed/25246523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.602326
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