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Structure-based analysis of the molecular interactions between acyltransferase and acyl carrier protein in vicenistatin biosynthesis

Acyltransferases (ATs) are key determinants of building block specificity in polyketide biosynthesis. Despite the importance of protein–protein interactions between AT and acyl carrier protein (ACP) during the acyltransfer reaction, the mechanism of ACP recognition by AT is not understood in detail....

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Miyanaga, Akimasa, Iwasawa, Shohei, Shinohara, Yuji, Kudo, Fumitaka, Eguchi, Tadashi
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763789/
https://ncbi.nlm.nih.gov/pubmed/26831085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1520042113
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