Lynx1 Shifts α4β2 Nicotinic Receptor Subunit Stoichiometry by Affecting Assembly in the Endoplasmic Reticulum

Glycosylphosphatidylinositol-anchored neurotoxin-like receptor binding proteins, such as lynx modulators, are topologically positioned to exert pharmacological effects by binding to the extracellular portion of nAChRs. These actions are generally thought to proceed when both lynx and the nAChRs are...

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Bibliografiska uppgifter
I publikationen:J Biol Chem
Huvudupphovsmän: Nichols, Weston A., Henderson, Brandon J., Yu, Caroline, Parker, Rell L., Richards, Christopher I., Lester, Henry A., Miwa, Julie M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2014
Ämnen:
Neurobiology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223341/
https://ncbi.nlm.nih.gov/pubmed/25193667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.573667
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