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Medroxyprogesterone Acetate Differentially Regulates Interleukin (IL)-12 and IL-10 in a Human Ectocervical Epithelial Cell Line in a Glucocorticoid Receptor (GR)-dependent Manner

Medroxyprogesterone acetate (MPA), designed to mimic the actions of the endogenous hormone progesterone (P(4)), is extensively used by women as a contraceptive and in hormone replacement therapy. However, little is known about the steroid receptor-mediated molecular mechanisms of action of MPA in th...

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Опубликовано в: :J Biol Chem
Главные авторы: Louw-du Toit, Renate, Hapgood, Janet P., Africander, Donita
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4223317/
https://ncbi.nlm.nih.gov/pubmed/25202013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.587311
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